2021 Spring Symposium




Tuesday, April 6, 2021

Virtual Symposium – Via Zoom Webinar 1:00 PM – 5:40 PM (EST)

Register Here

Register in advance for this webinar:


1:00 Introductory Remarks and first talk: Ramesh Shivdasani, MD, PhD – Dana-Farber, HMS

ISC candidates, executors, and transcriptional control


1:40 Ophir Klein, MD, PhD – University of California San Francisco

Regenerative strategies of the intestinal crypt


2:10 Frederic de Sauvage, PhD – Genentech

Role of intestinal stem cell plasticity in tumorigenesis


2:40 Kelley Yan, MD, PhD – Columbia College of Physicians & Surgeons

Wnt pathway regulation of intestinal stem cells


3:10 – 3:30 Break


3:30 Bruce Edgar, PhD – Huntsman Institute, University of Utah

Regeneration, tumorigenesis, and adaptive growth in the Drosophila intestine


4:00 Jason Spence, PhD – University of Michigan Medical School

Identifying intestinal stem cell niche factors in the developing human gut


4:30 Linda Samuelson, PhD – University of Michigan

Crypt cell remodeling and ISC niche regeneration after Notch inhibition


5:00 Omer Yilmaz, MD, PhD – Koch Center, MIT

Dietary control of stem cells in physiology and disease


5:30 Closing Remarks – Wayne Lencer, MD



Wayne Lencer, MD and Richard S. Blumberg, MD, Co-Hosts

Ramesh Shivdasani, MD, PhD, Scientific Host


HDDC Website: https://hddc.hms.harvard.edu/research

For additional information, contact: kebrewosen.densamo@childrens.harvard.edu


Co-Sponsored by: Harvard Stem Cell Institute


hddc_spring_symposium_agenda_-_tuesday_april_6_2021_flyer_01.pdf161 KB